NMR Processing

 

Introduction

The purpose of this page is to collect information on certain processing strategies, to outline their purpose, and to explain how to achieve this action using Bruker TopSpin. To that end, example spectra are provided for download, indicated by the Bruker TopSpin logo,

Outline

• Time-Domain Manipulations:
  
  • DC Offset Correction of the FID
  • First-Point Correction
  • Convolution
  • Zero-Filling
  • Linear Prediction
• Frequency-Domain Manipulations:
  • Phase Correction
  • Baseline Correction
  • Peak Picking
• Miscellaneous Manipulations:
  • convert TopSpin t1peaks.txt to spread-sheet type
  • generate an optimized VD list for T1 experiments
  • add a series of FIDs

Time-Domain Manipulations

	DC Offset Correction of the FID A constant voltage offset of the FID in the real or imaginary part will cause a "peak" exactly in the middle of the spectrum.
	First-Point Correction Fourier-transformation is geared towards periodic functions and has problems at discontinuities.
	Convolution What is frequently dubbed "convolution" actually is a multiplication of the FID with an appropriate filter function. The corresponding process in the frequency domain is called convolution.
	Zero-Filling
	Linear Prediction

Frequency-Domain Manipulations

	Phase Correction
	Baseline Correction
	Peak Picking Not really a manipulation, but part of the analysis. Routine, so who cares? But it looks like it is still an art, and proves: "know thy tools"

 

Miscellaneous Manipulations

• convert TopSpin t1peaks.txt to spread-sheet type
• generate an optimized VD list for T1 experiments
• add a series of FIDs